F-53B (6:2 chlorinated polyfluorinated ether sulfonate)

CAS: 73606-19-6 | Type: organic_pollutant

High Risk (Adults)

Safety Summary

Hazard ProfileChinese PFAS alternative to PFOS used in chrome plating since the 1970s. Structurally similar to PFOS but with ether linkage and chlorine. Detected in Chinese drinking water, river water, and human blood. Bioaccumulation factor comparable to or exceeding PFOS. Emerging global contaminant — detected outside China via consumer product imports.

Risk (Adults)High

Risk (Children)Very High

Risk (Dogs)Moderate To High

Risk (Cats)Moderate To High

Regulatory Status

SummaryNo major regulatory flags

Molecular FormulaC8ClF16KO4S

Molecular Weight570.67

Sources

No citations are recorded specifically for the human adult context, so the record-wide source list is shown. It backs the record, not this particular band.

F-53B as a chlorinated polyfluoroether-sulfonate AFFF replacement in China REVIEW · 2013
ECHA REACH evaluation of 6:2 chlorinated polyfluoroether sulfonate (F-53B) REGULATORY · 2021
OEHHA Proposition 65 List of Carcinogens or Reproductive Toxicants (CSV, list date 31-Jul-26) REGULATORY
PubChem computed properties for CID 25210512 (computed, not measured; as recorded by PubChem) DATABASE · 2026
PubChem computed structure descriptors for CID 25210512 (computed, not measured; as recorded by PubChem) DATABASE · 2026

Same data as the API response, which is open and needs no key. The full per-record source list is available to authenticated callers.

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