α-Thujone

Safety Summary

Regulatory Status

Sources

No citations are recorded specifically for the human adult context, so the record-wide source list is shown. It backs the record, not this particular band.

• PubChem Compound Database DATABASE · 2026
• FDA 21 CFR 172.510 — Thujone permitted in food only when present in plant materials (Artemisia + Salvia + Salvia officinalis at <10 ppm thujone-equivalents in finished food); banned as added pure substance REGULATORY · 2018
• IFRA Standard 51st Amendment — α + β-Thujone in fragrance products (GABA-A antagonist convulsant restriction; finished-product limits per product category) REGULATORY · 2024
• EFSA Scientific Opinion on α + β-Thujone (FGE.31 — Maximum permitted levels in alcoholic beverages 35 mg/L spirits ≤25% alcohol + 10 mg/L bitters / 5 mg/L liqueurs and dietary food) REGULATORY · 2016
• EU Regulation (EC) No 1334/2008 on flavourings — α + β-Thujone maximum permitted concentrations in absinthe + bitter alcoholic beverages REGULATORY · 2008
• Höld KM, Sirisoma NS, Ikeda T, Narahashi T, Casida JE — α-Thujone (the active component of absinthe): γ-aminobutyric acid type A receptor modulation and metabolic detoxification (mechanism + LD50 + chronic-cohort framework, PNAS) STUDY · 2000
• Consolidated TEXT: 32008R1334 — EN — 16.02.2026 REGULATORY
• PubChem computed properties for CID 261491 (computed, not measured; as recorded by PubChem) DATABASE · 2026
• TEDX List of Potential Endocrine Disruptors, full export (Excel from the publisher's own search, operator-saved 2026-10-08; list last updated September 2018) REFERENCE_DATABASE
• OEHHA Proposition 65 List of Carcinogens or Reproductive Toxicants (CSV, list date 31-Jul-26) REGULATORY
• where to look Human Metabolome Database (HMDB), as recorded by PubChem (Experimental Properties, CID 261491; where-to-look, not a source of this value) DATABASE · 2026
• PubChem computed structure descriptors for CID 261491 (computed, not measured; as recorded by PubChem) DATABASE · 2026

Same data as the API response, which is open and needs no key. The full per-record source list is available to authenticated callers.