Beta-carotene (E160a; provitamin A)

Safety Summary

Regulatory Status

Sources

No citations are recorded specifically for the human adult context, so the record-wide source list is shown. It backs the record, not this particular band.

• Beta-Carotene E160a CAS 7235-40-7 CI Food Orange 5 All-Trans C40H56 Provitamin A Carotenoid; ATBC 1994 Finland N=29133 Male Smokers 20mg/day RR 1.18 16% Lung Cancer Increase; CARET 1996 USA N=18314 Smokers Asbestos Workers 30mg Beta-Carotene + 25000IU Retinol RR 1.28 28% Lung Cancer Trial Stopped Early; IARC Monograph Vol 100E 2012 Supplementation High-Dose Smokers; Mechanism Pro-Oxidant Beta-Apocarotenoxy CYP1A2 Retinoid Signaling RAR RXR P450; FDA GRAS 21 CFR 73.95 Exempt Color; EFSA ADI Not Specified Group; Dunaliella Salina Algal Production Blakeslea Trispora Fungal; BCMO1 Regulated Conversion No Vitamin A Toxicity From Beta-Carotene; Carotenodermia Orange Skin Benign Reversible; Protective Dietary Non-Supplement Non-Smoker Inverse Association Lung Cancer; Margarine Primary Food Application EU; WHO Pregnancy Vitamin A Deficiency Preferred Form REGULATORY · 2012
• Computational Toxicology and Exposure APIs: Data Domains (EPA CCTE) REGULATORY
• CompTox Chemicals Dashboard: Release Notes (EPA) REGULATORY
• identity database ECHA CHEM, Download all substances: REACH registrations (ECHA's own list of REACH-registered substances) REGULATORY · 2026
• PubChem computed properties for CID 5280489 (computed, not measured; as recorded by PubChem) DATABASE · 2026
• OEHHA Proposition 65 List of Carcinogens or Reproductive Toxicants (CSV, list date 31-Jul-26) REGULATORY
• Permissible Exposure Limits – OSHA Annotated Table Z-1 REGULATORY
• where to look Hazardous Substances Data Bank (HSDB), as recorded by PubChem (Experimental Properties, CID 5280489; where-to-look, not a source of this value) DATABASE · 2026
• where to look DrugBank, as recorded by PubChem (Experimental Properties, CID 5280489; where-to-look, not a source of this value) DATABASE · 2026
• EPA CompTox CTX API: predicted properties for DTXSID3020253 (Beta-carotene (E160a; provitamin A)) REFERENCE
• PubChem computed structure descriptors for CID 5280489 (computed, not measured; as recorded by PubChem) DATABASE · 2026

Same data as the API response, which is open and needs no key. The full per-record source list is available to authenticated callers.