Retinoic acid (tretinoin)

Safety Summary

Regulatory Status

Sources

No citations are recorded specifically for the human adult context, so the record-wide source list is shown. It backs the record, not this particular band.

• US EPA Retinoic Acid/Tretinoin: Group D Not Classifiable Carcinogen; FDA Pregnancy Category X Confirmed Human Teratogen; Retinoid Embryopathy; Prescription Acne and Photoaging Drug; APL Differentiation Therapy; Topical Systemic Absorption Low; iPLEDGE Program Isotretinoin REGULATORY · 2000
• EFSA/SCCS Retinoic Acid: Prohibited in EU Cosmetics; Vitamin A Precursor Limits for Cosmetics; Retinoid Embryopathy Craniofacial Cardiac CNS; Retinoic Acid Receptor Hox Gene Disruption; Aquatic Endocrine Disruption Fish Larvae; Surface Water Detection Post-WWTP REGULATORY · 2010
• where to look PubChem: Toxicity section (CID 444795) PUBCHEM
• Computational Toxicology and Exposure APIs: Data Domains (EPA CCTE) REGULATORY
• CompTox Chemicals Dashboard: Release Notes (EPA) REGULATORY
• PubChem computed properties for CID 444795 (computed, not measured; as recorded by PubChem) DATABASE · 2026
• OEHHA Proposition 65 List of Carcinogens or Reproductive Toxicants (CSV, list date 31-Jul-26) REGULATORY
• where to look EPA ECOTOX Knowledgebase ASCII release ecotox_ascii_09_15_2026 DATABASE
• TEDX List of Potential Endocrine Disruptors, full export (Excel from the publisher's own search, operator-saved 2026-10-08; list last updated September 2018) REFERENCE_DATABASE
• Permissible Exposure Limits – OSHA Annotated Table Z-1 REGULATORY
• where to look CAMEO Chemicals, as recorded by PubChem (Experimental Properties, CID 444795; where-to-look, not a source of this value) DATABASE · 2026
• EPA CompTox CTX API: predicted properties for DTXSID7021239 (Retinoic acid (tretinoin)) REFERENCE
• PubChem computed structure descriptors for CID 444795 (computed, not measured; as recorded by PubChem) DATABASE · 2026

Same data as the API response, which is open and needs no key. The full per-record source list is available to authenticated callers.