Safrole

Safety Summary

Regulatory Status

Sources

No citations are recorded specifically for the human adult context, so the record-wide source list is shown. It backs the record, not this particular band.

• IARC Monographs Volume 10: Some Naturally Occurring Substances IARC_MONOGRAPH · 1972
• US EPA: Safrole — Group B2 Probable Human Carcinogen; Hepatocarcinogenesis; DNA Adducts at Guanine; Black Pepper and Star Anise Dietary Occurrence; MDMA Precursor DEA Scheduling; EU Flavoring Restrictions REGULATORY · 1986
• PROPOSITION 65 LIST OF CARCINOGENS OR REPRODUCTIVE TOXICANTS REGULATORY · 2026
• IARC Monographs, List of Classifications REGULATORY · 2026
• Substances Listed in the Fifteenth Report on Carcinogens REGULATORY
• where to look IARC Monographs — Monographs available (index) REGULATORY · 2026
• where to look PubChem: Toxicity section (CID 5144) PUBCHEM
• Computational Toxicology and Exposure APIs: Data Domains (EPA CCTE) REGULATORY
• CompTox Chemicals Dashboard: Release Notes (EPA) REGULATORY
• PubChem computed properties for CID 5144 (computed, not measured; as recorded by PubChem) DATABASE · 2026
• where to look EPA ECOTOX Knowledgebase ASCII release ecotox_ascii_09_15_2026 DATABASE
• Permissible Exposure Limits – OSHA Annotated Table Z-1 REGULATORY
• where to look CAMEO Chemicals, as recorded by PubChem (Experimental Properties, CID 5144; where-to-look, not a source of this value) DATABASE · 2026
• EPA CompTox CTX API: predicted properties for DTXSID0021254 (Safrole) REFERENCE
• ECHA Annex VI to CLP: the unofficial Excel table (up to and including the 23rd ATP) REGULATORY
• PubChem computed structure descriptors for CID 5144 (computed, not measured; as recorded by PubChem) DATABASE · 2026
• Regulation (EC) No 1272/2008 of the European Parliament and of the Council of 16 December 2008 on classification, labelling and packaging of substances and mixtures, amending and repealing Directives 67/548/EEC and 1999/45/EC, and amending Regulation (EC) No 1907/2006: Annex VI, Part 3, Table 3.1 (Official Journal L 353, 31.12.2008) REGULATORY · 2008

Same data as the API response, which is open and needs no key. The full per-record source list is available to authenticated callers.