4,4'-Methylenedianiline (MDA)

Safety Summary

Regulatory Status

Sources

No citations are recorded specifically for the human adult context, so the record-wide source list is shown. It backs the record, not this particular band.

• IARC Monographs Volume 39: 4,4'-Methylenedianiline (MDA) — Group 2B; Hepatocellular Carcinomas and Thyroid Tumors in Rodents; Epping Jaundice Hepatotoxicity; MDI Precursor IARC_MONOGRAPH · 1986
• Kopelman et al.: Epping Jaundice — Hepatitis from MDA-Contaminated Flour; 84 Cases; Cholestatic Pattern; Dose-Response; First Evidence of MDA Human Hepatotoxicity STUDY · 1966
• OSHA Standard 29 CFR 1910.1050: 4,4'-Methylenedianiline — PEL 0.01 ppm; Carcinogen Designation; Skin Absorption; Medical Surveillance; Epoxy Curing Industry Requirements REGULATORY · 1992
• Consolidated TEXT: 32006R1907 — EN — 22.06.2026 REGULATORY
• PROPOSITION 65 LIST OF CARCINOGENS OR REPRODUCTIVE TOXICANTS REGULATORY · 2026
• IARC Monographs, List of Classifications REGULATORY · 2026
• ECHA Annex VI to CLP: the unofficial Excel table (up to and including the 23rd ATP) (secondary: unofficial by its own statement) REGULATORY
• identity database ECHA CHEM, Download all substances: REACH registrations (ECHA's own list of REACH-registered substances) REGULATORY · 2026
• where to look PubChem: Toxicity section (CID 7577) PUBCHEM
• Computational Toxicology and Exposure APIs: Data Domains (EPA CCTE) REGULATORY
• CompTox Chemicals Dashboard: Release Notes (EPA) REGULATORY
• NIOSH Pocket Guide to Chemical Hazards: 4,4'-Methylenedianiline (npgd0415) REGULATORY
• Consolidated TEXT: 32004L0037 — EN — 08.04.2024 REGULATORY
• Toxicological Profile for Methylenedianiline (ATSDR, August 1998) ASSESSMENT
• PubChem computed properties for CID 7577 (computed, not measured; as recorded by PubChem) DATABASE · 2026
• where to look CAMEO Chemicals, as recorded by PubChem (Experimental Properties, CID 7577; where-to-look, not a source of this value) DATABASE · 2026
• where to look Haz-Map, Information on Hazardous Chemicals and Occupational Diseases, as recorded by PubChem (Experimental Properties, CID 7577; where-to-look, not a source of this value) DATABASE · 2026
• where to look Occupational Safety and Health Administration (OSHA), as recorded by PubChem (Experimental Properties, CID 7577; where-to-look, not a source of this value) DATABASE · 2026
• EPA CompTox CTX API: predicted properties for DTXSID6022422 (4,4'-Methylenedianiline (MDA)) REFERENCE
• PubChem computed structure descriptors for CID 7577 (computed, not measured; as recorded by PubChem) DATABASE · 2026

Same data as the API response, which is open and needs no key. The full per-record source list is available to authenticated callers.