4,4'-Methylene bis(2-chloroaniline) (MOCA)
CAS: 101-14-4 | Type: monomer
Severe Risk (Adults)
Safety Summary
Hazard Profilehazardous
Risk (Adults)Severe
Regulatory Status
SummaryIARC: Group 1 | California Prop 65 listed | REACH SVHC (Candidate List) | REACH Annex XIV: authorisation required
Molecular FormulaC13H12Cl2N2
Molecular Weight267.15
Food Safety Thresholds (Baby Food)
CA_Prop65 — SubstanceNo level set (disclosure mandate, not a level)
Governance status, not safety advice — see the full coverage-gap & legal-force matrix.
Sources
No citations are recorded specifically for the human adult context, so the record-wide source list is shown. It backs the record, not this particular band.
- IARC Monographs Volume 100F (2012): MOCA (4,4′-methylenebis(2-chloroaniline)) — Group 1, carcinogenic to humans (upgraded from Group 2A, Vol 57 1993, in Vol 99 2010) IARC_MONOGRAPH · 2012
- NIOSH Special Hazard Review with Control Recommendations: 4,4′-Methylenebis(2-chloroaniline) (MOCA) (DHEW/NIOSH Pub. 78-188) REGULATORY · 1978
- ATSDR Toxicological Profile for 4,4′-Methylenebis(2-chloroaniline) (MBOCA = MOCA, CAS 101-14-4) REGULATORY · 1994
- Consolidated TEXT: 32006R1907 — EN — 22.06.2026 REGULATORY
- PROPOSITION 65 LIST OF CARCINOGENS OR REPRODUCTIVE TOXICANTS REGULATORY · 2026
- IARC Monographs, List of Classifications REGULATORY · 2026
- identity database ECHA CHEM, Download all substances: REACH registrations (ECHA's own list of REACH-registered substances) REGULATORY · 2026
- where to look PubChem: Toxicity section (CID 7543) PUBCHEM
- Computational Toxicology and Exposure APIs: Data Domains (EPA CCTE) REGULATORY
- CompTox Chemicals Dashboard: Release Notes (EPA) REGULATORY
- NIOSH Pocket Guide to Chemical Hazards - 4,4'-Methylenebis(2-chloroaniline) REGULATORY
- Toxicological Profile for 4,4’-Methylenebis(2-chloroaniline) (MBOCA) (ATSDR, October 2017) ASSESSMENT
- Consolidated TEXT: 32004L0037 — EN — 08.04.2024 REGULATORY
- Provisional Peer-Reviewed Toxicity Values for 4,4'-Methylenebis(2-chloroaniline) (MOCA) (CASRN 101-14-4), EPA/690/R-06/021F, Final, 8-3-2006 ASSESSMENT
- PubChem computed properties for CID 7543 (computed, not measured; as recorded by PubChem) DATABASE · 2026
- where to look CAMEO Chemicals, as recorded by PubChem (Experimental Properties, CID 7543; where-to-look, not a source of this value) DATABASE · 2026
- where to look ILO-WHO International Chemical Safety Cards (ICSCs), as recorded by PubChem (Experimental Properties, CID 7543; where-to-look, not a source of this value) DATABASE · 2026
- EPA CompTox CTX API: predicted properties for DTXSID5020865 (4,4'-Methylene bis(2-chloroaniline) (MOCA)) REFERENCE
- ECHA Annex VI to CLP: the unofficial Excel table (up to and including the 23rd ATP) REGULATORY
- PubChem computed structure descriptors for CID 7543 (computed, not measured; as recorded by PubChem) DATABASE · 2026
Same data as the API response, which is open and needs no key. The full per-record source list is available to authenticated callers.
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