Chlordecone (Kepone)
CAS: 143-50-0
High Risk (Adults)
Safety Summary
Hazard Profilehazardous
Risk (Adults)High
Risk (Children)High
Regulatory Status
SummaryIARC: Group 2B | California Prop 65 listed | Stockholm Convention listed
NGO listOn the TEDX List of Potential Endocrine Disruptors (The Endocrine Disruption Exchange, a non-governmental list; last updated September 2018). This is a list membership, not a regulatory classification. Source: the TEDX List export (publisher's page)
Molecular FormulaC10Cl10O
Molecular Weight490.6
Sources
No citations are recorded specifically for the human adult context, so the record-wide source list is shown. It backs the record, not this particular band.
- IARC Monographs Volume 20: Chlordecone (Kepone) — Group 2B; hepatocellular carcinomas in mice; inadequate human carcinogenicity evidence; Hopewell worker episode data IARC_MONOGRAPH · 1979
- US EPA: James River/Chesapeake Bay Kepone Contamination — Worker Neurotoxicity, Fishing Ban 1975–1988, Aquatic Toxicity Assessment, Point Source Remediation REGULATORY · 1976
- French Ministry of Health: Chlordécone Plan — Martinique and Guadeloupe Contamination Assessment, Food Exposure, TIMOUN Birth Cohort, Prostate Cancer Risk, Soil Remediation Research REGULATORY · 2008
- Stockholm Convention on Persistent Organic Pollutants — Chlordecone Annex A listing (eliminated globally; COP-4 Geneva 2009; canonical POPs designation framework alongside lindane + alpha-HCH + beta-HCH + pentachlorobenzene) REGULATORY · 2009
- NIOSH Pocket Guide to Chemical Hazards — Chlordecone (REL 0.001 mg/m³ TWA; 'Ca' carcinogen designation; Hopewell-Virginia 1975 LSP-manufacturing-incident cohort framework) REGULATORY · 2019
- ATSDR Toxicological Profile for Mirex and Chlordecone (CERCLA Substance Priority List; James River + Lake Onondaga sediment-contamination + bioaccumulation + biomagnification cohort framework) REGULATORY · 1995
- PROPOSITION 65 LIST OF CARCINOGENS OR REPRODUCTIVE TOXICANTS REGULATORY · 2026
- IARC Monographs, List of Classifications REGULATORY · 2026
- Substances Listed in the Fifteenth Report on Carcinogens REGULATORY
- Chlordecone (Kepone) | CASRN 143-50-0 | DTXSID1020770 | IRIS | US EPA, ORD REGULATORY
- where to look PubChem: Toxicity section (CID 299) PUBCHEM
- NIOSH Pocket Guide to Chemical Hazards - Kepone REGULATORY
- Computational Toxicology and Exposure APIs: Data Domains (EPA CCTE) REGULATORY
- CompTox Chemicals Dashboard: Release Notes (EPA) REGULATORY
- Stockholm Convention: All POPs (the Convention's own list of listed chemicals, Annexes A, B and C) REGULATORY
- Stockholm Convention: The New POPs (the Convention's own index of listed chemicals) REGULATORY
- ES/ER/TM-86/R3 Toxicological Benchmarks for Wildlife: 1996 Revision (DOE/ORNL) STUDY
- Toxicological Profile for Mirex and Chlordecone ASSESSMENT
- EPA ToxRefDB 3.0 point-of-departure release (pod.csv) DATABASE
- Stockholm Convention on Persistent Organic Pollutants: text with Annexes (2025 English) REGULATORY
- where to look EPA ECOTOX Knowledgebase ASCII release ecotox_ascii_09_15_2026 DATABASE
- TEDX List of Potential Endocrine Disruptors, full export (Excel from the publisher's own search, operator-saved 2026-10-08; list last updated September 2018) REFERENCE_DATABASE
- Permissible Exposure Limits – OSHA Annotated Table Z-1 REGULATORY
- where to look CAMEO Chemicals, as recorded by PubChem (Experimental Properties, CID 299; where-to-look, not a source of this value) DATABASE · 2026
- where to look Haz-Map, Information on Hazardous Chemicals and Occupational Diseases, as recorded by PubChem (Experimental Properties, CID 299; where-to-look, not a source of this value) DATABASE · 2026
- where to look Hazardous Substances Data Bank (HSDB), as recorded by PubChem (Experimental Properties, CID 299; where-to-look, not a source of this value) DATABASE · 2026
- EPA CompTox CTX API: predicted properties for DTXSID1020770 (Chlordecone (Kepone)) REFERENCE
- ECHA Annex VI to CLP: the unofficial Excel table (up to and including the 23rd ATP) REGULATORY
- PubChem computed structure descriptors for CID 299 (computed, not measured; as recorded by PubChem) DATABASE · 2026
- Regulation (EC) No 1272/2008 of the European Parliament and of the Council of 16 December 2008 on classification, labelling and packaging of substances and mixtures, amending and repealing Directives 67/548/EEC and 1999/45/EC, and amending Regulation (EC) No 1907/2006: Annex VI, Part 3, Table 3.1 (Official Journal L 353, 31.12.2008) REGULATORY · 2008
Same data as the API response, which is open and needs no key. The full per-record source list is available to authenticated callers.
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