Spinosad

Safety Summary

Regulatory Status

Sources

No citations are recorded specifically for the human adult context, so the record-wide source list is shown. It backs the record, not this particular band.

• US EPA: Spinosad Registration Review — biological insecticide (Saccharopolyspora spinosa fermentation); IRAC Group 5; nAChR + GABA chloride channel mechanism; bee acute contact toxicity; aquatic invertebrate toxicity; organic certification; pet product safety (Comfortis, Trifexis); human lice treatment; label timing restrictions for pollinator protection (2019) REGULATORY · 2019
• ASPCA Animal Poison Control Center: Neonicotinoid Insecticide Toxicosis — imidacloprid, nitenpyram, dinotefuran; pet product safety (Advantage, Capstar, Vectra); nAChR mechanism; mammalian vs. insect selectivity; clinical signs and management (2023) VETERINARY · 2023
• identity database ECHA CHEM, Download all substances: REACH registrations (ECHA's own list of REACH-registered substances) REGULATORY · 2026
• OEHHA Proposition 65 List of Carcinogens or Reproductive Toxicants (CSV, list date 31-Jul-26) REGULATORY
• Permissible Exposure Limits – OSHA Annotated Table Z-1 REGULATORY
• EPA ToxRefDB 3.0 point-of-departure release (pod.csv) DATABASE
• PubChem computed properties for CID 17754356 (computed, not measured; as recorded by PubChem) DATABASE · 2026
• where to look DrugBank, as recorded by PubChem (Experimental Properties, CID 17754356; where-to-look, not a source of this value) DATABASE · 2026
• where to look ILO-WHO International Chemical Safety Cards (ICSCs), as recorded by PubChem (Experimental Properties, CID 17754356; where-to-look, not a source of this value) DATABASE · 2026
• 40 CFR Part 180 (eCFR text as of 24 September 2026): § 180.495 Spinosad; tolerances for residues. REGULATORY
• PubChem computed structure descriptors for CID 17754356 (computed, not measured; as recorded by PubChem) DATABASE · 2026

Same data as the API response, which is open and needs no key. The full per-record source list is available to authenticated callers.