Sulfamethoxazole

Safety Summary

Regulatory Status

Sources

These citations are the ones recorded for the human adult context.

• FDA Prescribing Information: TMP-SMX (Bactrim/Septra) — UTI/PCP/MRSA; SJS/TEN risk; sulfonamide allergy; neonatal kernicterus contraindication; G6PD hemolysis; HIV hypersensitivity; photosensitivity; crystalluria hydration; leucovorin antidote (2023) REGULATORY · 2023
• WHO AWaRe Classification of Antibiotics — Access/Watch/Reserve categories; stewardship framework; amoxicillin Access category; ciprofloxacin/azithromycin Watch; vancomycin Reserve; resistance drivers; outpatient prescribing guidance (2023) REGULATORY · 2023
• IARC Monographs, List of Classifications REGULATORY · 2026
• where to look PubChem: Toxicity section (CID 5329) PUBCHEM
• TEDX List of Potential Endocrine Disruptors, full export (Excel from the publisher's own search, operator-saved 2026-10-08; list last updated September 2018) REFERENCE_DATABASE
• OEHHA Proposition 65 List of Carcinogens or Reproductive Toxicants (CSV, list date 31-Jul-26) REGULATORY
• Permissible Exposure Limits – OSHA Annotated Table Z-1 REGULATORY
• EPA CompTox CTX API: predicted properties for DTXSID8026064 (Sulfamethoxazole) REFERENCE

Same data as the API response, which is open and needs no key. The full per-record source list is available to authenticated callers.