Methyl ethyl ketone

Safety Summary

Regulatory Status

Sources

These citations are the ones recorded for the human adult context.

• NIOSH Pocket Guide: Methyl Ethyl Ketone (MEK) — IDLH 3000 ppm; PEL 200 ppm; n-hexane neuropathy potentiation via CYP2E1; coating/adhesive uses; flash point −9°C; A4 carcinogen classification (2019) REGULATORY · 2019
• EPA: Methyl Ethyl Ketone — VOC ozone formation; GRAS food flavoring; printing ink solvent; auto refinishing; shoe industry neuropathy outbreaks from MEK+hexane mixtures (2020) REGULATORY · 2020
• Methyl ethyl ketone (MEK) | CASRN 78-93-3 | DTXSID3021516 | IRIS | US EPA, ORD REGULATORY
• 29 CFR 1910.1000, Tables Z-1 and Z-2 (eCFR editorial compilation, as of 2026-09-22) REGULATORY
• identity database ECHA CHEM, Download all substances: REACH registrations (ECHA's own list of REACH-registered substances) REGULATORY · 2026
• where to look PubChem: Toxicity section (CID 6569) PUBCHEM
• Consolidated TEXT: 32000L0039 — EN — 20.05.2021 REGULATORY
• CDC - NIOSH Pocket Guide to Chemical Hazards - 2-Butanone REGULATORY
• OEHHA Proposition 65 List of Carcinogens or Reproductive Toxicants (CSV, list date 31-Jul-26) REGULATORY
• where to look CAMEO Chemicals, as recorded by PubChem (Experimental Properties, CID 6569; where-to-look, not a source of this value) DATABASE · 2026
• where to look Hazardous Substances Data Bank (HSDB), as recorded by PubChem (Experimental Properties, CID 6569; where-to-look, not a source of this value) DATABASE · 2026
• EPA CompTox CTX API: predicted properties for DTXSID3021516 (Methyl ethyl ketone) REFERENCE
• ECHA Annex VI to CLP: the unofficial Excel table (up to and including the 23rd ATP) REGULATORY

Same data as the API response, which is open and needs no key. The full per-record source list is available to authenticated callers.