Salicylic acid

Safety Summary

Regulatory Status

Sources

These citations are the ones recorded for the human adult context.

• FDA OTC Monograph: Salicylic Acid — acne (0.5–2%); wart removal (up to 40%); dandruff (1.8–3%); Reye's syndrome warning; systemic absorption from large-area application; methyl salicylate poisoning (2019) REGULATORY · 2019
• NIOSH: Salicylic Acid — keratolytic mechanism; dermal absorption ~25%; salicylism at high serum levels; topical analgesic products; aspirin relationship; pediatric precautions (2019) REGULATORY · 2019
• identity database ECHA CHEM, Download all substances: REACH registrations (ECHA's own list of REACH-registered substances) REGULATORY · 2026
• where to look PubChem: Toxicity section (CID 338) PUBCHEM
• TEDX List of Potential Endocrine Disruptors, full export (Excel from the publisher's own search, operator-saved 2026-10-08; list last updated September 2018) REFERENCE_DATABASE
• OEHHA Proposition 65 List of Carcinogens or Reproductive Toxicants (CSV, list date 31-Jul-26) REGULATORY
• Permissible Exposure Limits – OSHA Annotated Table Z-1 REGULATORY
• where to look DrugBank, as recorded by PubChem (Experimental Properties, CID 338; where-to-look, not a source of this value) DATABASE · 2026
• where to look Hazardous Substances Data Bank (HSDB), as recorded by PubChem (Experimental Properties, CID 338; where-to-look, not a source of this value) DATABASE · 2026
• EPA CompTox CTX API: predicted properties for DTXSID7026368 (Salicylic acid) REFERENCE
• ECHA Annex VI to CLP: the unofficial Excel table (up to and including the 23rd ATP) REGULATORY

Same data as the API response, which is open and needs no key. The full per-record source list is available to authenticated callers.