Acetone

Safety Summary

Regulatory Status

Sources

These citations are the ones recorded for the human adult context.

• NIOSH Pocket Guide: Acetone — IDLH 2500 ppm; PEL 1000 ppm; CNS narcosis at high concentrations; nail salon occupational exposure; ketone body metabolism; non-carcinogen (2019) REGULATORY · 2019
• EPA VOC Exemption Decision: Acetone — negligible photochemical reactivity; exempt from VOC regulations; consumer product safety; endogenous production; GRAS food additive status (2004) REGULATORY · 2004
• § 1910.1000 Air contaminants. REGULATORY
• Acetone | CASRN 67-64-1 | DTXSID8021482 | IRIS | US EPA, ORD REGULATORY
• identity database ECHA CHEM, Download all substances: REACH registrations (ECHA's own list of REACH-registered substances) REGULATORY · 2026
• where to look PubChem: Toxicity section (CID 180) PUBCHEM
• NIOSH Pocket Guide to Chemical Hazards: Acetone (npgd0004) REGULATORY
• Consolidated TEXT: 32000L0039 — EN — 20.05.2021 REGULATORY
• OEHHA Proposition 65 List of Carcinogens or Reproductive Toxicants (CSV, list date 31-Jul-26) REGULATORY
• where to look CAMEO Chemicals, as recorded by PubChem (Experimental Properties, CID 180; where-to-look, not a source of this value) DATABASE · 2026
• where to look Hazardous Substances Data Bank (HSDB), as recorded by PubChem (Experimental Properties, CID 180; where-to-look, not a source of this value) DATABASE · 2026
• EPA CompTox CTX API: predicted properties for DTXSID8021482 (Acetone) REFERENCE
• ECHA Annex VI to CLP: the unofficial Excel table (up to and including the 23rd ATP) REGULATORY

Same data as the API response, which is open and needs no key. The full per-record source list is available to authenticated callers.