Ketamine

Safety Summary

Regulatory Status

Sources

These citations are the ones recorded for the human adult context.

• US DEA: Ketamine — Schedule III Controlled Substance, Veterinary and Medical Anesthesia Uses, Ketamine-Induced Uropathy Epidemiology, Recreational Misuse Trends, and Hepatotoxicity Reports (2022) REGULATORY · 2022
• US FDA: Esketamine (Spravato) — Approval for Treatment-Resistant Depression (2019), Pediatric Brain Development Advisory (2016, General Anesthetic Agents in Children <3 Years), REMS Program, and Ketamine Compounding for Depression (2023) REGULATORY · 2023
• identity database ECHA CHEM, Download all substances: REACH registrations (ECHA's own list of REACH-registered substances) REGULATORY · 2026
• OEHHA Proposition 65 List of Carcinogens or Reproductive Toxicants (CSV, list date 31-Jul-26) REGULATORY
• Permissible Exposure Limits – OSHA Annotated Table Z-1 REGULATORY
• EPA CompTox CTX API: predicted properties for DTXSID8023187 (Ketamine) REFERENCE

Same data as the API response, which is open and needs no key. The full per-record source list is available to authenticated callers.