Sodium cyclamate (cyclamate) Safety Profile

Sources

These citations are the ones recorded for the human adult context.

US FDA: Sodium Cyclamate — 1969 Prohibition Order, Bladder Tumor Rat Study Basis, Subsequent Petitions for Re-approval, and Current Banned Status in US Food Supply (2022 status update) REGULATORY · 2022
EFSA Panel on Food Additives: Re-evaluation of Cyclamate (E952) — ADI 7 mg/kg bw/day, Cyclohexylamine Metabolite Assessment, Safety Confirmation at Dietary Exposure Levels (EFSA Journal 2009;96) REGULATORY · 2009
WHO JECFA: Cyclamate and Sodium Cyclamate — Safety Evaluation, ADI 11 mg/kg bw/day (as cyclamic acid equivalent), Global Regulatory Status, and Repeated Confirmation of Safety at Permitted Use Levels (2019) REGULATORY · 2019
IARC Monographs, List of Classifications REGULATORY · 2026
identity database ECHA CHEM, Download all substances: REACH registrations (ECHA's own list of REACH-registered substances) REGULATORY · 2026
OEHHA Proposition 65 List of Carcinogens or Reproductive Toxicants (CSV, list date 31-Jul-26) REGULATORY
Permissible Exposure Limits – OSHA Annotated Table Z-1 REGULATORY
EPA CompTox CTX API: predicted properties for DTXSID6020355 (Sodium cyclamate (cyclamate)) REFERENCE

Same data as the API response, which is open and needs no key. The full per-record source list is available to authenticated callers.