Sildenafil (PDE5 inhibitors)

Safety Summary

Regulatory Status

Sources

These citations are the ones recorded for the human adult context.

• US FDA: Sildenafil (Viagra/Revatio) Prescribing Information — Erectile Dysfunction, Pulmonary Arterial Hypertension, Nitrate Contraindication, and Cardiovascular Risk REGULATORY · 2020
• ASPCA Animal Poison Control Center: Sildenafil and PDE5 Inhibitor Toxicosis in Dogs — Hypotension, Clinical Signs, and Supportive Management VETERINARY · 2023
• OEHHA Proposition 65 List of Carcinogens or Reproductive Toxicants (CSV, list date 31-Jul-26) REGULATORY
• Permissible Exposure Limits – OSHA Annotated Table Z-1 REGULATORY
• EPA CompTox CTX API: predicted properties for DTXSID6023579 (Sildenafil (PDE5 inhibitors)) REFERENCE

Same data as the API response, which is open and needs no key. The full per-record source list is available to authenticated callers.