1,4-Dioxane

Safety Summary

Regulatory Status

Sources

These citations are the ones recorded for the human adult context.

• IARC Monographs Volume 71: Re-evaluation of Some Organic Chemicals, Hydrazine and Hydrogen Peroxide — 1,4-Dioxane Group 2B Evaluation REGULATORY · 1999
• 1,4-Dioxane | CASRN 123-91-1 | DTXSID4020533 | IRIS | US EPA, ORD REGULATORY
• § 1910.1000 Air contaminants. REGULATORY
• 1,4-Dioxane; CASRN 123-91-1 REGULATORY
• 2018 Edition of the Drinking Water Standards and Health Advisories Tables REGULATORY
• PROPOSITION 65 LIST OF CARCINOGENS OR REPRODUCTIVE TOXICANTS REGULATORY · 2026
• IARC Monographs, List of Classifications REGULATORY · 2026
• Substances Listed in the Fifteenth Report on Carcinogens REGULATORY
• ECHA Annex VI to CLP: the unofficial Excel table (up to and including the 23rd ATP) (secondary: unofficial by its own statement) REGULATORY
• identity database ECHA CHEM, Download all substances: REACH registrations (ECHA's own list of REACH-registered substances) REGULATORY · 2026
• NIOSH Pocket Guide to Chemical Hazards - Dioxane REGULATORY
• Industry Code of Practice on Chemicals Classification and Hazard Communication (DOSH Malaysia) REGULATORY
• where to look PubChem: Toxicity section (CID 31275) PUBCHEM
• Consolidated TEXT: 32009L0161 — EN — 21.08.2018 REGULATORY
• where to look Hazardous Substances Data Bank (HSDB), as recorded by PubChem (Experimental Properties, CID 31275; where-to-look, not a source of this value) DATABASE · 2026
• EPA CompTox CTX API: predicted properties for DTXSID4020533 (1,4-Dioxane) REFERENCE

Same data as the API response, which is open and needs no key. The full per-record source list is available to authenticated callers.