Perfluorooctane sulfonic acid (PFOS)

Safety Summary

Regulatory Status

Food Safety Thresholds (Baby Food)

Governance status, not safety advice — see the full coverage-gap & legal-force matrix.

Sources

These citations are the ones recorded for the human adult context.

• IARC Monographs Volume 135: Perfluorooctanoic Acid (PFOA) and Perfluorooctane Sulfonic Acid (PFOS) — Group 1/2B Evaluation: PFOA classified Group 1 (carcinogenic to humans), PFOS classified Group 2B (possibly carcinogenic to humans) REGULATORY · 2023
• US EPA: National Primary Drinking Water Regulation for PFAS — Maximum Contaminant Level Goals and MCLs for PFOA, PFOS, and Four Other PFAS (Final Rule) REGULATORY · 2024
• US EPA: PFAS Strategic Roadmap — EPA's Commitments to Action 2021–2024 (PFOS/PFOA Priority Designation and Regulatory Framework) REGULATORY · 2021
• IARC Monographs, List of Classifications REGULATORY · 2026
• where to look PubChem: Toxicity section (CID 74483) PUBCHEM
• OEHHA Proposition 65 List of Carcinogens or Reproductive Toxicants (CSV, list date 31-Jul-26) REGULATORY
• Permissible Exposure Limits – OSHA Annotated Table Z-1 REGULATORY
• TEDX List of Potential Endocrine Disruptors, full export (Excel from the publisher's own search, operator-saved 2026-10-08; list last updated September 2018) REFERENCE_DATABASE
• where to look Hazardous Substances Data Bank (HSDB), as recorded by PubChem (Experimental Properties, CID 74483; where-to-look, not a source of this value) DATABASE · 2026
• Toxicological Profile for Perfluoroalkyls (ATSDR, Released May 2021) ASSESSMENT
• EPA CompTox CTX API: predicted properties for DTXSID3031864 (Perfluorooctane sulfonic acid (PFOS)) REFERENCE
• ECHA Annex VI to CLP: the unofficial Excel table (up to and including the 23rd ATP) REGULATORY

Same data as the API response, which is open and needs no key. The full per-record source list is available to authenticated callers.