Arsenic trioxide

Safety Summary

Regulatory Status

Sources

No citations are recorded specifically for the human adult context, so the record-wide source list is shown. It backs the record, not this particular band.

• ATSDR Toxicological Profile — CAS 1327-53-3 REFERENCE
• IARC Monographs Volume 100C (2012) — Arsenic and Inorganic Arsenic Compounds Group 1 Carcinogenic to Humans (sufficient evidence for lung + skin + urinary-bladder cancer; arsenic-trioxide + arsenate + arsenite + arsine framework) REGULATORY · 2012
• FDA Prescribing Information — Arsenic Trioxide (Trisenox) for Acute Promyelocytic Leukemia (APL; FDA approved 2000; PML-RARA t(15;17) APL induction + consolidation framework; QT-prolongation + APL-differentiation-syndrome boxed warning) REGULATORY · 2018
• US EPA IRIS — Inorganic Arsenic (oral cancer slope factor 1.5 (mg/kg-day)⁻¹; inhalation unit risk 4.3E-3 (µg/m³)⁻¹; SMCL + MCL 10 µg/L drinking-water framework + Bangladesh-Taiwan-Argentina-Chile epidemiology cohorts) REGULATORY · 2010
• ATSDR Toxicological Profile for Arsenic (top-priority pollutant ranked #1 CERCLA Substance Priority List; smelter + glass + agricultural-pesticide + drinking-water cohort framework + chronic + acute exposure pathways) REGULATORY · 2007
• NIOSH Pocket Guide to Chemical Hazards — Arsenic and inorganic compounds (REL 0.002 mg As/m³ Ceiling 15-min; 'Ca' carcinogen designation; Class A1 confirmed human carcinogen; smelter + arsenical-pesticide + microelectronics-cohort framework) REGULATORY · 2019
• Smith AH, Marshall G, Yuan Y et al. — Increased mortality from lung cancer and bronchiectasis in young adults after exposure to arsenic in utero and in early childhood (canonical Region II Antofagasta Chile cohort framework driving IARC-100C reaffirmation, EHP) STUDY · 2006
• Consolidated TEXT: 32006R1907 — EN — 22.06.2026 REGULATORY
• PubChem computed properties for CID 14888 (computed, not measured; as recorded by PubChem) DATABASE · 2026
• OEHHA Proposition 65 List of Carcinogens or Reproductive Toxicants (CSV, list date 31-Jul-26) REGULATORY
• where to look CAMEO Chemicals, as recorded by PubChem (Experimental Properties, CID 14888; where-to-look, not a source of this value) DATABASE · 2026
• ECHA Annex VI to CLP: the unofficial Excel table (up to and including the 23rd ATP) REGULATORY
• PubChem computed structure descriptors for CID 14888 (computed, not measured; as recorded by PubChem) DATABASE · 2026
• Regulation (EC) No 1272/2008 of the European Parliament and of the Council of 16 December 2008 on classification, labelling and packaging of substances and mixtures, amending and repealing Directives 67/548/EEC and 1999/45/EC, and amending Regulation (EC) No 1907/2006: Annex VI, Part 3, Table 3.1 (Official Journal L 353, 31.12.2008) REGULATORY · 2008

Same data as the API response, which is open and needs no key. The full per-record source list is available to authenticated callers.